Zbornik Matice srpske za prirodne nauke 2007 Issue 113, Pages: 249-254
https://doi.org/10.2298/ZMSPN0713249S
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Experimentally induced dermatomycoses at rats and treatment with Lavandula angustifolia essential oil
Soković Marina D. 
(Institut za biološka istraživanja "Siniša Stanković", Beograd)
Glamočlija Jasmina M. (Institut za biološka istraživanja 'Siniša Stanković', Beograd)
Marin Petar D. (Biološki fakultet,Institut za botaniku, Beograd)
Brkić Dejan D. (Johnson & Johnson S.E., Beograd)
Vukojević Jelena B. (Biološki fakultet,Institut za botaniku, Beograd)
Jovanović Dragutin (Vojno-medicinska akademija,Centar za preventivnu medicinu, Beograd)
Bulajić Nina (Vojno-medicinska akademija,Centar za preventivnu medicinu, Beograd)
Kataranovski Dragan S. (Institut za biološka istraživanja 'Siniša Stanković', Beograd)
The in vivo evaluation of antifungal activity of the Lavandula angustifolia essential oil was made on two-month old male Wistar rats. We examined the therapeutic potency against experimentally induced dermatomycoses in rats using the most frequent dermatomycetes, Trichophyton mentagrophytes. The therapeutic efficacy of 1% solution of essential oil as well as commercial preparation-bifonazole, was evaluated. During the 13-day observation period the oil-treated animals were cured completely.
Keywords: essential oil, Lavandula angustifolia, Dermatomycetes, antufungal activity