Veterinarski glasnik 2024 Volume 78, Issue 2, Pages: 117-130
https://doi.org/10.2298/VETGL240602013N
Full text ( 497 KB)


Impact of garlic polysulfide supplementation on biochemical and hematological parameters in dairy cows

Nedić Sreten ORCID iD icon (University of Belgrade, Faculty of Veterinary Medicine, Department of Ruminants and Swine diseases, Belgrade, Serbia), sreten.nedic@vet.bg.ac.rs
Gajić Mirjana ORCID iD icon (University of Belgrade, Faculty of Veterinary Medicine, Department of Ruminants and Swine diseases, Belgrade, Serbia)
Bošnjaković Dušan ORCID iD icon (University of Belgrade, Faculty of Veterinary Medicine, Department of Physiology and Biochemistry, Belgrade, Serbia)
Vujanac Ivan ORCID iD icon (University of Belgrade, Faculty of Veterinary Medicine, Department of Ruminants and Swine diseases, Belgrade, Serbia)
Prodanović Radiša ORCID iD icon (University of Belgrade, Faculty of Veterinary Medicine, Department of Ruminants and Swine diseases, Belgrade, Serbia)
Bojkovski Jovan ORCID iD icon (University of Belgrade, Faculty of Veterinary Medicine, Department of Physiology and Biochemistry, Belgrade, Serbia)
Mitrović Aleksandra ORCID iD icon (University of Belgrade, Faculty of Veterinary Medicine, Department of Ruminants and Swine diseases, Belgrade, Serbia)
Milenković Milan ORCID iD icon (Institute of Public Health of Serbia “Dr Milan Jovanović Batut”, Center for Hygiene and Human Ecology, Belgrade, Serbia)
Manojlović Dragan ORCID iD icon (South Ural State University, Chelyabinsk, Russia + Center for New Technologies, Belgrade, Serbia)
Jovanović Ljubomir ORCID iD icon (University of Belgrade, Faculty of Veterinary Medicine, Department of Physiology and Biochemistry, Belgrade, Serbia)
Kirovski Danijela ORCID iD icon (University of Belgrade, Faculty of Veterinary Medicine, Department of Physiology and Biochemistry, Belgrade, Serbia)
Arsić Sveta ORCID iD icon (University of Belgrade, Faculty of Veterinary Medicine, Department of Ruminants and Swine diseases, Belgrade, Serbia)

In recent years, there have been numerous research activities related to the use of different herbal agents, especially those originating from chestnuts and garlic, as alternatives to synthetic growth promoters like antibiotics. Garlic and its active ingredients have been studied for their potential benefits, such as improving feed intake, production performance, rumen fermentation, and udder health. The aim of our study was to investigate the influence of garlic polysulfides, including diallyl polysulfide and dipropyl polysulfide, on hematological and biochemical parameters in dairy cows, as well as their possible effect on subclinical mastitis therapy. Eighteen late lactation Holstein cows were divided into three numerically equal groups (n=6): CON (non-supplemented cows), ALL (supplemented with 1000 mg/day of diallyl polysulfide), and PRP (supplemented with 1000 mg/day of dipropyl polysulfide). Blood sampling for hematological and biochemical analyses as well as the California mastitis test (CMT) test were performed before and after the 15-day study. The results showed that garlic supplementation significantly increased blood leukocyte count and blood glucose concentration (p<0.05, respectively), and significantly decreased blood urea concentration (p<0.05) after the 15-day trial in both ALL and PRP groups compared with the day 0. In the supplemented groups, the CMT score was significantly lower (p<0.05, respectively) after the 15-day treatment compared with the CON group. The use of different mixtures of biologically active garlic polysulfides in the diet could improve immune and metabolic status, as well as support mastitis treatments in dairy cows.

Keywords: dairy cows, garlic polysulfides, blood parameters, CMT score

Project of the Ministry of Science, Technological Development and Innovation, Republic of Serbia, Grant no. 451-03-66/2024-03/200143

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